Human primary lymphocyte colony formation in agar culture: polyclonal origin and significance.
作者信息
Farcet J P, Testa U
出版信息
Exp Hematol. 1982 Feb;10(2):172-7.
PMID:6977457
Abstract
Primary human lymphocyte colonies, which grow on the surface of agar culture under PHA stimulation, arise from more than one progenitor cell: they contain both type A and B of G6PD when the donor is heterozygous for the isoenzymes. The distribution pattern of electrophoretic bands indicates that, on the average, two T lymphocyte clones proliferate per colony. Colony formation in the present circumstances appears as an in vitro system more suitable for the study of cellular cooperation between a limited number of cells than for the characterization of immature lymphocyte precursors in man.
摘要
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