Queneau P, Gabbai A, Perpoint B, Salque J R, Laurent H, Decousus H, Boucheron S
Rev Rhum Mal Osteoartic. 1982 Feb;49(2):111-9.
Using their own personal series of 19 cases of leprosy complicated by massive osteolysis (AO), along with a comparison of these cases with data from previously published reports, the authors review the principal clinical and radiological findings of these manifestations which are not observed except in cases of leprosy where neuropathy is present, even though other factors (perforating plantar ulcers, poor hygiene, traumatisms) may play a contributing role independent of possible interference from non specific osteoarthritis or Hansen's bacilla, itself. After reviewing other causes of massive osteolysis and discussing the pathogeny of these manifestations during leprosy, the authors refer to the various therapies which can prevent or stabilize osteolysis or aid the patient to better tolerate its manifestations.
作者利用他们自己收集的19例麻风病合并大块骨质溶解（AO）的病例，并将这些病例与先前发表报告中的数据进行比较，回顾了这些表现的主要临床和放射学特征。这些特征仅在存在神经病变的麻风病病例中出现，尽管其他因素（足底穿通性溃疡、卫生条件差、外伤）可能独立发挥作用，而不受非特异性骨关节炎或麻风杆菌本身可能产生的干扰。在回顾了大块骨质溶解的其他病因并讨论了麻风病期间这些表现的发病机制后，作者提及了各种可预防或稳定骨质溶解或帮助患者更好耐受其表现的治疗方法。
