Dubord P J, Krachmer J H
Arch Ophthalmol. 1982 May;100(5):788-90. doi: 10.1001/archopht.1982.01030030792013.
Seven children from two unrelated families had lattice corneal dystrophy. Their ages ranged from 3 to 13 years at initial examination. The children were observed for an average of 35 months. Three distinct early slitlamp characteristics were found. The first characteristic was subepithelial white opacities that were discrete, round or ovoid, nonrefractile, nonstaining, variably sized (estimated at 0.1 to 0.5 mm), and larger than the previously reported minute refractile dots. The second finding was a diffuse axial anterior stromal haze that was either the initial sign or developed in conjunction with the other two characteristics. The third finding was anterior stromal dots and filamentary lines that were refractile on indirect slitlamp illumination and white on direct illumination. Knowledge of these three slitlamp characteristics in conjunction with examination of older family members wil facilitate the early diagnosis of lattice corneal dystrophy.
来自两个无亲缘关系家庭的七名儿童患有格子状角膜营养不良。初次检查时，他们的年龄在3岁至13岁之间。这些儿童平均被观察了35个月。发现了三个明显的早期裂隙灯特征。第一个特征是上皮下白色混浊，呈离散状、圆形或椭圆形，无屈光性，不着色，大小不一（估计为0.1至0.5毫米），且比先前报道的微小屈光性小点大。第二个发现是弥漫性轴向基质前层混浊，它要么是初始体征，要么与其他两个特征同时出现。第三个发现是基质前层小点和丝状线条，在间接裂隙灯照明下有屈光性，在直接照明下呈白色。了解这三个裂隙灯特征并结合对年长家庭成员的检查将有助于早期诊断格子状角膜营养不良。
