系统性红斑狼疮中的免疫性别差异及女性优势
Immunologic sex differences and the female predominance in systemic lupus erythematosus.
作者信息
Inman R D
出版信息
Arthritis Rheum. 1978 Sep-Oct;21(7):849-52. doi: 10.1002/art.1780210718.
PMID:697955
Abstract
The female predominance in many rheumatic disorders, most notably systemic lupus erythematosus, suggests that immunologic sex differences may modify susceptibility to disease. Clinical and experimental data indicate heightened humoral immunity and depressed cellular immunity in females compared with males. These differences appear to be mediated by sex hormones.
摘要
许多风湿性疾病中女性占主导地位，最显著的是系统性红斑狼疮，这表明免疫性别的差异可能会改变疾病易感性。临床和实验数据表明，与男性相比，女性的体液免疫增强而细胞免疫受到抑制。这些差异似乎是由性激素介导的。
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