两栖动物晶状体的辐射性白内障形成

Radiation cataractogenesis in the amphibian lens.

作者信息

Worgul B V, Rothstein H, Medvedovsky C, Merriam G R, Wilson M A

出版信息

Ophthalmic Res. 1982;14(2):73-82. doi: 10.1159/000265177.

Abstract

This report describes a reproducible and characteristic sequelae for radiation cataractogenesis in the amphibian. The development of lens opacification was investigated as a function of dose and time after X-irradiation of the eye of postmetamorphic bullfrogs. It was found that the development of radiation cataracts in frogs is both age and dose dependent. It was also determined that, far from being radiation resistant, frog lenses are sensitive to doses that are moderately cataractogenic for mammals.

摘要

本报告描述了两栖动物辐射性白内障形成的一种可重现的特征性后遗症。研究了变态后的牛蛙眼睛经X射线照射后晶状体混浊的发展情况与剂量和时间的关系。结果发现，青蛙辐射性白内障的发展既与年龄有关，也与剂量有关。还确定，青蛙晶状体远非抗辐射，而是对在哺乳动物中具有中度致白内障作用的剂量敏感。