耐利福平流感嗜血杆菌的出现。
Emergence of rifampin-resistant Haemophilus influenzae.
作者信息
Nicolle L E, Postl B, Kotelewetz E, Albritton W, Harding G K, Bourgault A M, Ronald A R
出版信息
Antimicrob Agents Chemother. 1982 Mar;21(3):498-500. doi: 10.1128/AAC.21.3.498.
Abstract
Rifampin susceptibility of nasopharyngeal Haemophilus influenzae strains was determined before and after community-wide chemoprophylaxis with rifampin (children) and sequential minocycline-rifampin (adults). All strains were rifampin susceptible before prophylaxis, but 10.3% of the strains at 1 week and 7.5% of the strains at 9 weeks after prophylaxis were rifampin resistant.
摘要
在社区范围内对儿童使用利福平进行化学预防以及对成人依次使用米诺环素 - 利福平进行化学预防之前和之后，测定了鼻咽部流感嗜血杆菌菌株对利福平的敏感性。在预防之前，所有菌株对利福平敏感，但在预防后1周时，10.3%的菌株对利福平耐药，在预防后9周时，7.5%的菌株对利福平耐药。
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