Sedlák J
Endocrinol Exp. 1982 Jun;16(2):103-9.
The changes in the level of sulfhydryl fractions in total adrenals were measured with the aid of Ellman's reagent [Sedlák and Lindsay 1968] in rats exposed either to stress by forced immobilization or by the injury in Noble-Collip drum. It was found that nonprotein sulfhydryl fraction (NP-SH) in rat adrenals is represented exclusively by SH-glutathione (GSH). Moreover, the increase of the concentration of GSH in adrenals was related to the time and number of exposures to stressor. The maximum enhancement of GSH in adrenals occurred when the animals were subjected to stress daily for 7 days. It is suggested that GSH may be involved in the steroidogenesis in the inhibition of nonenzymatic decarboxylation of DOPA and in the proteosynthesis in adrenals.
借助埃尔曼试剂[塞德拉克和林赛，1968年]，对通过强制固定或诺布尔-科利普滚筒损伤施加应激的大鼠的整个肾上腺中巯基组分水平的变化进行了测量。结果发现，大鼠肾上腺中的非蛋白巯基组分（NP-SH）仅由巯基谷胱甘肽（GSH）构成。此外，肾上腺中GSH浓度的增加与应激源暴露的时间和次数有关。当动物每天接受应激7天时，肾上腺中GSH的增加达到最大值。有人提出，GSH可能参与肾上腺中的类固醇生成，抑制多巴的非酶促脱羧反应，并参与肾上腺中的蛋白质合成。
