Jenkner F L, Schuhfried F
Appl Neurophysiol. 1981;44(5-6):330-7. doi: 10.1159/000102215.
A search has been made for an optimal wave form for transcutaneous nerve stimulation for pain. The effect of electrical stimulation of sympathetic nerves was studied as a model because (1) this system has small diameter axons, as do nociceptive fibers, and (2) alteration of activity in sympathetic fibers may be evaluated objectively by observing the effects upon circulation. A transcutaneously applied waveform was found which influenced circulation maximally, suggesting that sympathetic nerves were affected by the transdermal stimulation. The hypothesis that these stimulation parameters might be optimal for pain relief was tested. Relief of 40% or more was obtained in 68% of 2,800 patients suffering from chronic pain of diverse origin, utilizing this waveform.
人们一直在寻找用于经皮神经刺激以缓解疼痛的最佳波形。以交感神经的电刺激效果作为模型进行研究，原因如下：（1）该系统具有与伤害性纤维一样的小直径轴突，以及（2）交感纤维活动的改变可通过观察对循环系统的影响来客观评估。发现一种经皮施加的波形能最大程度地影响循环，这表明交感神经受到了经皮刺激的影响。对这些刺激参数可能是缓解疼痛的最佳参数这一假设进行了测试。利用这种波形，在2800名患有各种慢性疼痛的患者中，68%的患者疼痛缓解了40%或更多。
