Popov D V, Sokolova Z A, Kalistratova E N, Golichenkov V A, Starodubov S M
Arkh Anat Gistol Embriol. 1982 Jun;82(6):74-84.
Pigmentation of the cornea has been studied in the Rana temporaria larvae at the 22d-27th stages of development macroscopically (total corneal preparations with the surrounding skin) and microscopically. Dynamics of the pigment cells transfer that fill the transparent cornea is compared to the histological rearrangement of the latter. The corneal pigmentation is demonstrated to occur with a constant velosity and is well described by means of the linear regression equation. At initial stages of transformation, the corneal pigmentation overtakes the histological processes, then the two processes run in parallel and only towards the metamorphosis period the corneal histological changes slightly overtake the pigmentation process. As a whole, the pigment cells arrangement demonstrates the transformation degree of the external corneal into the skin after the eye has been extirpated. A suggestion is made explaining the necessity of a constant inducing retinal influence on the skin in Anura larvae.