Tanaka Y, Hazama H, Fukuhara T, Tsutsui T
Folia Psychiatr Neurol Jpn. 1982;36(2):137-43. doi: 10.1111/j.1440-1819.1982.tb00264.x.
A computerized tomography (CT) of the brain was carried out on 40 manic-depressive patients and 40 controls in order to study the organic characteristics of the brain in manic-depressive psychosis. In the age group of 49 years and below, the left septum-caudate distance (LSC) showed a lower value in the manic-depressive group, but the other measurements for the ventricular system did not differ between both groups. The age group of 50 and over revealed a significant enlargement of maximum width of the interhemispheric fissure (IF) and maximum width between the sylvian fissure and inner skull (SFIS) in the manic-depressive group compared with the controls. The tendency to an enlargement of the third ventricle (HIV) and maximum width of the right anterior horn (RAH) was also seen in the manic-depressive patients. Cortical atrophy tended to appear in the temporal and occipital lobes earlier in the manic-depressive group than in the controls. The patients showing a cerebral asymmetry of the hemisphere in the manic-depressive group tended to show a reversed cerebral asymmetry.
为研究躁狂抑郁症性精神病患者大脑的器质性特征，对40名躁狂抑郁症患者和40名对照者进行了脑部计算机断层扫描（CT）。在49岁及以下年龄组中，躁狂抑郁症组的左侧隔-尾状核距离（LSC）值较低，但两组间脑室系统的其他测量值并无差异。与对照组相比，50岁及以上年龄组中，躁狂抑郁症组的大脑半球间裂最大宽度（IF）和外侧裂与颅骨内面之间的最大宽度（SFIS）显著增大。躁狂抑郁症患者中也可见第三脑室（HIV）和右侧前角最大宽度（RAH）增大的趋势。与对照组相比，躁狂抑郁症组的颞叶和枕叶皮质萎缩出现得更早。躁狂抑郁症组中显示大脑半球不对称的患者往往表现出相反的大脑不对称。
