Phenotypic diversity of T cell leukemias.

A series of monoclonal antibodies and additional selective markers (e.g. TdT) have been used to describe the detailed composite phenotypes expressed by cells in 172 cases of T cell leukemia. The results provide further evidence for a striking correlation between phenotype, maturation arrest, and clinical subgroup, and have important implications for our understanding of the origins of T cell malignancy.