Lenzi G L
Arch Ital Biol. 1982 May;120(1-3):189-200.
The "brain work" is characterized by an input which is the processing of sensory information and by an output consisting in the production of ideo-motor activities. This work is performed through electrochemical mechanisms. These biologic mechanisms are strictly dependent on the continuous arrival at regional level of sufficient amounts of glucose and oxygen through blood flow. In fact the regional level of function determines the amount of blood flow and therefore of substrates to that region. This close relationship, function-blood flow-metabolism, permits the study of the cerebral function at any of these three levels. Neurophysiologists recording neuronal firing and clinicians assessing regional levels of blood flow and metabolism activities are seeing very specular aspects of cerebral physiology. The application to the human being of the techniques for regional quantitation of blood flow and of glucose (or oxygen) consumption offers to physiologists and clinicians a new possibility for understanding cerebral functioning both in health and disease.
“脑力工作”的特点是其输入为感觉信息的处理，输出是观念运动活动的产生。这项工作通过电化学机制来完成。这些生物学机制严格依赖于通过血流持续向局部区域输送足够量的葡萄糖和氧气。事实上，局部功能水平决定了该区域的血流量，进而决定了底物的量。这种功能-血流-代谢之间的密切关系使得能够在这三个层面中的任何一个层面研究脑功能。记录神经元放电的神经生理学家和评估局部血流及代谢活动水平的临床医生所看到的是脑生理学中非常相似的方面。将血流量和葡萄糖（或氧气）消耗的区域定量技术应用于人类，为生理学家和临床医生提供了一个理解健康和疾病状态下脑功能的新机会。
