表皮细胞产物的免疫调节：ETAF在炎症性和肿瘤性皮肤病中的可能作用。
Immune modulation by epidermal cell products: possible role of ETAF in inflammatory and neoplastic skin diseases.
作者信息
Sauder D N, Katz S I
出版信息
J Am Acad Dermatol. 1982 Nov;7(5):651-4. doi: 10.1016/s0190-9622(82)70145-8.
PMID:6982907
Abstract
Recent studies have indicated that the epidermis plays an important role in the modulation of immunologic reactions. The factors involved in these processes include not only Langerhans cells but also keratinocyte products. One of these products, ETAF (Epidermal cell derived Thymocyte Activating Factor), which is similar to the macrophage derived product interleukin 1 (IL-1), is reviewed. Speculations as to its possible role in skin diseases are presented.
摘要
最近的研究表明，表皮在免疫反应的调节中起重要作用。参与这些过程的因素不仅包括朗格汉斯细胞，还包括角质形成细胞产物。本文对其中一种产物——表皮细胞衍生的胸腺细胞激活因子（ETAF）进行了综述，该因子与巨噬细胞衍生的产物白细胞介素1（IL-1）相似。文中还提出了关于其在皮肤病中可能作用的推测。
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