脑萎缩。一种免疫紊乱疾病？
Cerebral atrophy. An immunological disorder?
作者信息
Janković B D, Jakulić S, Horvat J
出版信息
Lancet. 1977 Jul 30;2(8031):219-20. doi: 10.1016/s0140-6736(77)92835-5.
PMID:69830
Abstract
Patients with cerebral atrophy of unknown origin, patients with nuclear forms of schizophrenia or neurosis, and normal subjects were skin-tested with human brain and liver proteins. The frequency of positive delayed skin-sensitivity reactions to brain proteins was significantly higher in the cerebral-atrophy group than in other groups, thus suggesting a correlation between cerebral atrophy and cell-mediated immunity.
摘要
对不明原因脑萎缩患者、核型精神分裂症或神经症患者以及正常受试者进行人脑和肝蛋白的皮肤试验。脑萎缩组对脑蛋白延迟性皮肤敏感反应阳性的频率显著高于其他组，这表明脑萎缩与细胞介导免疫之间存在关联。
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引用本文的文献
1
Hypersensitivity to human brain S-100 protein in chronic alcoholics.慢性酒精中毒患者对人脑S-100蛋白的超敏反应。
Clin Exp Immunol. 1982 Sep;49(3):598-602.
2
Schizophrenia and other psychiatric diseases: evidence for neurotissue hypersensitivity.精神分裂症及其他精神疾病：神经组织超敏反应的证据
Clin Exp Immunol. 1980 Jun;40(3):515-22.
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