Densert B, Densert O
Laryngoscope. 1982 Nov;92(11):1285-92. doi: 10.1288/00005537-198211000-00012.
Influence of ambient pressure changes on the hearing levels in Meniere's disease was previously demonstrated, using a pressure chamber. The present report concerns a new method for management of Meniere's disease by local application of overpressure. The experimental background and methodologic considerations in therapy are summarized. Five illustrative cases of verified Meniere's disease are presented. The patients had advanced, nonfluctuating hearing loss and incapacitating vestibular symptoms. Long periods of remission were obtained in all cases. Improvement of hearing was a major clinical consideration in the treatment. Use of local overpressure seems to offer possibilities of improving hearing even in advanced stages of Meniere's disease. Despite the disabling pretreatment hearing loss, hearing in these 5 patients was restored to normal or serviceable levels. The follow-up period was about 2 years from start of treatment.
先前曾使用压力舱证明了环境压力变化对梅尼埃病听力水平的影响。本报告涉及一种通过局部施加超压来治疗梅尼埃病的新方法。总结了该治疗方法的实验背景和方法学考量。文中呈现了5例经证实的梅尼埃病典型病例。这些患者存在重度、稳定的听力损失以及使人丧失能力的前庭症状。所有病例均获得了长时间的缓解。听力改善是治疗中的主要临床考量因素。局部超压的使用似乎为改善梅尼埃病晚期的听力提供了可能。尽管这些患者在治疗前存在严重的听力损失，但这5例患者的听力恢复到了正常或可用水平。从治疗开始起的随访期约为2年。
