Ettinger L J, Torrisi J, Wood B P, Anderson V M
Med Pediatr Oncol. 1982;10(5):477-81. doi: 10.1002/mpo.2950100508.
Until recently, Pneumocystis carinii pneumonitis was the most common cause of death in patients with leukemia in remission. Prior to the advent of effective antimicrobial agents, this disease was virtually 100% fatal in the cancer patient undergoing immunosuppressive therapy. The spontaneous improvement of P carinii pneumonitis in a child with acute lymphocytic leukemia suggests a higher incidence of P carinii pneumonitis in immunocompromised patients than is commonly realized.
直到最近,卡氏肺孢子虫肺炎仍是缓解期白血病患者最常见的死亡原因。在有效的抗菌药物出现之前,这种疾病在接受免疫抑制治疗的癌症患者中几乎100%致命。一名急性淋巴细胞白血病患儿的卡氏肺孢子虫肺炎自发好转,这表明免疫功能低下患者中卡氏肺孢子虫肺炎的发病率比通常认为的要高。