Kopteva L A, Zhevaliukova L I, Biriuzova V I
Biull Eksp Biol Med. 1978 Sep;86(9):295-7.
The effect of acute experimental heart ischemia on protein synthesis and RNA of the internal membranes of myocardial mitochondria was studied; there was a sharp increase in the protein synthesizing system activity of the internal mitochondrial membranes. The most pronounced protein and PNA exchange was noted on the 7th day of the infarction; apparently it was the most critical time in the development of the given pathological process. A study of ultrastructure of mitochondrial membranes in the course of experimental infarction development demonstrated marked changes in their ultrastructure depending on the severity of the disease.
研究了急性实验性心脏缺血对心肌线粒体内膜蛋白质合成及核糖核酸的影响；线粒体内膜蛋白质合成系统的活性急剧增加。在梗死第7天观察到最显著的蛋白质和核糖核酸交换；显然这是给定病理过程发展中最关键的时期。对实验性梗死发展过程中线粒体膜超微结构的研究表明，其超微结构根据疾病严重程度有明显变化。
