Willer Jean-Claude, Roby Agnès, Boulu Philippe, Boureau François
Laboratoire de Physiologie, Faculté de Médecine Saint-Antoine, 27, rue Chaligny, 75571 Paris Cedex 12 France.
Pain. 1982 Nov;14(3):267-278. doi: 10.1016/0304-3959(82)90133-6.
The effects of low frequency (2 Hz) high intensity (10-12 mA) (electroacupuncture, EA) and of high frequency (100 Hz) low intensity (2 mA) (transcutaneous nerve stimulation, TNS) conditioning stimuli were studied on the nociceptive component (R2) of the blink reflex in normal volunteers. EA induced a progressive and moderate partially naloxone-reversible depression in the R2 response. In contrast, TNS induced a rapid and major depression in this reflex. In this latter case, naloxone failed to produce any reversal effect. These two patterns of data are discussed and further electrophysiological studies provide some evidence for two different mechanisms in the depressive effects of EA and TNS upon the nociceptive component of the blink reflex in man.
在正常志愿者中，研究了低频（2赫兹）高强度（10 - 12毫安）（电针，EA）和高频（100赫兹）低强度（2毫安）（经皮神经刺激，TNS）条件刺激对眨眼反射伤害性成分（R2）的影响。电针在R2反应中诱导出一种渐进性且中度的、部分可被纳洛酮逆转的抑制作用。相比之下，经皮神经刺激在该反射中诱导出快速且显著的抑制作用。在后一种情况下，纳洛酮未能产生任何逆转效应。对这两种数据模式进行了讨论，进一步的电生理研究为电针和经皮神经刺激对人类眨眼反射伤害性成分的抑制作用存在两种不同机制提供了一些证据。
