Wakefield D, Penny R
Aust J Ophthalmol. 1982 Nov;10(4):277-81. doi: 10.1111/j.1442-9071.1982.tb01630.x.
Toxoplasma gondii, due to its ability to escape and modify the normal immune response, is able to survive within the retina indefinitely with the production of an occasional acute inflammatory response. The cellular immune system is mainly responsible for limiting infection. Diagnosis is based on clinical features coupled with measurements of antibody response (systemic and ocular) and cell mediated immunity. The treatment of toxoplasma chorioretinitis when indicated should be specific and immunosuppressive agents should only be used in conjunction with antibiotics to avoid dissemination of the organism.
由于能够逃避和改变正常免疫反应,弓形虫能够在视网膜内存活,偶尔引发急性炎症反应。细胞免疫系统主要负责限制感染。诊断基于临床特征,结合抗体反应(全身和眼部)测量以及细胞介导免疫检测。有指征时,弓形虫脉络膜视网膜炎的治疗应具有特异性,免疫抑制剂仅应与抗生素联合使用,以避免病原体扩散。