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[流感嗜血杆菌:对12种抗生素的敏感性,根据荚膜血清型、生物型及分离来源进行分析,以及流行病学意义]

[Haemophilus influenzae: sensitivity to 12 antibiotics, analysis according to capsular serotype, biotype and source of isolation, and epidemiologic implications].

作者信息

Pinon G

出版信息

Ann Microbiol (Paris). 1982 Nov-Dec;133(3):415-25.

PMID:6984598
Abstract

A total of 129 strains of Haemophilus influenzae were tested for susceptibility to twelve antibiotics. Capsular serotypes and biotypes were determined, and the relation between these parameters and minimal inhibitory concentrations (MIC) were analysed. Non-capsulated strains were more susceptible to streptomycin than capsulated ones. The distribution of MIC of chloramphenicol among biotypes was different. The distribution of MIC of penicillin G, tetracycline and chloramphenicol among sources of isolation was also different. Therefore the strains did not have the same origin, and one should look at the concept of organotropism for H. influenzae.

摘要

共对129株流感嗜血杆菌进行了12种抗生素的药敏试验。确定了荚膜血清型和生物型,并分析了这些参数与最低抑菌浓度(MIC)之间的关系。非荚膜菌株比荚膜菌株对链霉素更敏感。氯霉素的MIC在生物型之间的分布不同。青霉素G、四环素和氯霉素的MIC在分离源之间的分布也不同。因此,这些菌株并非同源,对于流感嗜血杆菌应考虑器官嗜性的概念。

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