McLarty D G, Ratcliffe W A, Ratcliffe J G, Shimmins J G, Goldberg A
Br J Psychiatry. 1978 Sep;133:211-8. doi: 10.1192/bjp.133.3.211.
The prevalence of abnormal serum total thyroxine (T4) and triiodothyronine (T3) concentrations were determined in 1,206 in-patients in two associated psychiatric hospitals. The biochemical pattern of primary hypothyroidism occurred in five females and one male (prevalence 0.5 per cent), but in only one patient was the diagnosis clinically obvious. Eight patients (all female) were clinically hyperthyroid (prevalence 0.7 per cent), of whom six were previously undiagnosed. There was no evidence that phenothiazines or benzodiazepine therapy had any significant effect on thyroid hormone levels. The small differences in thyroid hormone levels between psychiatric diagnostic groups could be explained by differences in age distribution.
在两家相关精神病医院的1206名住院患者中测定了血清总甲状腺素（T4）和三碘甲状腺原氨酸（T3）浓度异常的患病率。原发性甲状腺功能减退的生化模式出现在5名女性和1名男性中（患病率为0.5%），但只有1例患者临床诊断明显。8名患者（均为女性）临床甲状腺功能亢进（患病率为0.7%），其中6例以前未被诊断。没有证据表明吩噻嗪类或苯二氮䓬类治疗对甲状腺激素水平有任何显著影响。精神科诊断组之间甲状腺激素水平的微小差异可以用年龄分布的差异来解释。
