Zornoza G, Hernández J L, Sanz M L, Fernández J, Goena I, Lera J M
Rev Esp Oncol. 1981;28(1):17-27.
The authors study the amount of B cells and serum immunoglobulins in patients with mammary cancer or fibrocystic disease. They indicate that a decreasing in B cells and IgG, and an increasing in IgA are associated with a better prognosis. There is an inverse relation between the level of serum IgG and the blastic transformation of T cells by PHA, what is an indirect measure of the circulating IgG immune complexes. The presence of B cells with IgG in their surfaces makes worse the prognosis.
作者研究了乳腺癌或纤维囊性疾病患者体内B细胞和血清免疫球蛋白的数量。他们指出,B细胞和IgG减少,而IgA增加与较好的预后相关。血清IgG水平与PHA诱导的T细胞母细胞转化之间存在负相关,这是循环IgG免疫复合物的一种间接测量方法。表面带有IgG的B细胞的存在会使预后变差。