Soifer L, Andreozzi E, Dávalos J
Acta Gastroenterol Latinoam. 1982;12(4):377-81.
By means of fiberendoscopic injection sclerotherapy, it was possible to achieve eradication of esophageal varices in 18 patients. At the onset of treatment 9 patients had small varices (grade II) and other 9 had big varices (grade III). It was found in the big varices group there was needed more courses (p less than 0.01) and a greater amount of sclerosing agent (p less than 0.001) than in the group with small varices. Since those patients with big varices required more courses and more volume of sclerosing agent, and in fact they have more risk to rebleed during the pre-eradication period. It is proposed as a solution during this period, the use of a B receptor blocking agent (Propranolol) simultaneously with sclerotherapy.
通过纤维内镜注射硬化疗法，18例患者的食管静脉曲张得以根除。治疗开始时，9例患者有小静脉曲张（II级），另外9例有大静脉曲张（III级）。结果发现，大静脉曲张组比小静脉曲张组需要更多疗程（p<0.01）和更大剂量的硬化剂（p<0.001）。由于大静脉曲张患者需要更多疗程和更大剂量的硬化剂，实际上他们在根除前期再出血的风险更高。建议在此期间，在硬化疗法的同时使用β受体阻滞剂（普萘洛尔）作为一种解决方案。
