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肾移植失败后原位保留的同种异体肾。

Renal allografts retained in situ after failure.

作者信息

Silberman H, Fitzgibbons T J, Butler J, Berne T V

出版信息

Arch Surg. 1980 Jan;115(1):42-3. doi: 10.1001/archsurg.1980.01380010034006.

DOI:10.1001/archsurg.1980.01380010034006
PMID:6985790
Abstract

Twenty-four renal allografts functioning up to six years from the date of transplantation were retained in situ from four days to five years following return of the patient to hemodialysis. Fifteen of the 24 kidneys were removed for specific indications within four days to ten months. The reasons for allograft nephrectomy included fever, hematuria, graft pain and tenderness, and severe hypertension. Nine patients remained asymptomatic with grafts retained three months to five years (median, two years) following return to hemodialysis. It appears safe to retain nonfunctioning grafts in asymptomatic patients, thereby avoiding an unnecessary operation when failure is due to chronic rejection or recurrent glomerulonephritis. Nevertheless, in many patients complications eventually develop for which the allograft will be removed.

摘要

24例肾移植受者在移植后肾功能良好达6年,在患者恢复血液透析后4天至5年内将移植肾原位保留。24例中有15例在4天至10个月内因特定指征而切除移植肾。移植肾切除的原因包括发热、血尿、移植肾疼痛和压痛以及严重高血压。9例患者在恢复血液透析后3个月至5年(中位时间为2年)内移植肾保留且无症状。在无症状患者中保留无功能的移植肾似乎是安全的,从而在移植肾因慢性排斥或复发性肾小球肾炎而功能衰竭时避免不必要的手术。然而,许多患者最终会出现并发症,届时移植肾将被切除。

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Renal allografts retained in situ after failure.肾移植失败后原位保留的同种异体肾。
Arch Surg. 1980 Jan;115(1):42-3. doi: 10.1001/archsurg.1980.01380010034006.
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Renal allograft fracture: clinicopathological study of 21 cases.肾移植同种异体肾骨折:21例临床病理研究
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引用本文的文献

1
Nephrectomy Versus Embolization of Non-Functioning Renal Graft: A Systematic Review with a Proportional Meta-Analysis.肾切除术与无功能肾移植栓塞术的比较:一项采用比例Meta分析的系统评价
Ann Transplant. 2018 Mar 27;23:207-217. doi: 10.12659/AOT.907700.
2
Early but not late allograft nephrectomy reduces allosensitization after transplant failure.移植肾失功后早期而非晚期切除移植肾可减少同种致敏。
Can Urol Assoc J. 2011 Dec;5(6):E142-7. doi: 10.5489/cuaj.10032. Epub 2011 Mar 1.
3
Transplant nephrectomy improves survival following a failed renal allograft.
移植肾切除术可改善移植肾失功患者的生存。
J Am Soc Nephrol. 2010 Feb;21(2):374-80. doi: 10.1681/ASN.2009050480. Epub 2009 Oct 29.