来自哺乳动物组织的低分子量铁结合因子，可增强细菌生长。
Low molecular weight iron-binding factor from mammalian tissue that potentiates bacterial growth.
作者信息
Jones R L, Peterson C M, Grady R W, Cerami A
出版信息
J Exp Med. 1980 Feb 1;151(2):418-28. doi: 10.1084/jem.151.2.418.
Abstract
A low molecular weight, iron-binding factor was isolated from horse liver. This host-associated iron transfer factor (HAITF) is capable of binding iron and stimulating bacterial growth by promoting iron uptake into bacteria. Also, when injected into infected animals, HAITF increases the virulence of bacterial infections. HAITF bioactivity is ubiquitous in animal tissues and present in serum. It is proposed that HAITF is a factor that inadvertently plays a role in the host-parasite competition for iron.
摘要
一种低分子量的铁结合因子从马肝脏中分离出来。这种宿主相关的铁转运因子（HAITF）能够结合铁，并通过促进铁进入细菌来刺激细菌生长。此外，当注入受感染的动物体内时，HAITF会增加细菌感染的毒力。HAITF的生物活性在动物组织中普遍存在且存在于血清中。有人提出，HAITF是一种在宿主与寄生虫争夺铁的过程中不经意间发挥作用的因子。
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