急性运动对肥胖人群单核细胞胰岛素结合的影响。

Effects of acute exercise on insulin binding to monocytes in obesity.

作者信息

Koivisto V A, Soman V R, Felig P

出版信息

Metabolism. 1980 Feb;29(2):168-72. doi: 10.1016/0026-0495(80)90142-0.

Abstract

The effect of 3 hr of cycle erogmeter exercise on 125I-insulin binding to monocytes was studied in obese and 10 nonobese control subjects. In the basal state before exercise, total specific 125I-insulin binding to monocytes in obese subjects (4.8% +/- 0.3%) was 25% lower than in control subjects (6.6% +/- 0.4%, p less than 0.01). During exercise, insulin binding increased in both groups (p less than 0.05), but the rise in obese subjects was minimal (13% +/- 1%) and was 60%--70% lower than in controls (36% +/- 3%, p less than 0.01). The data indicate that the increment in insulin binding to monocytes induced by acute exercise is diminished in obesity.

摘要

研究了3小时的周期测力计运动对肥胖受试者和10名非肥胖对照受试者单核细胞125I胰岛素结合的影响。在运动前的基础状态下，肥胖受试者单核细胞的总特异性125I胰岛素结合率（4.8%±0.3%）比对照受试者（6.6%±0.4%，p<0.01）低25%。运动期间，两组的胰岛素结合均增加（p<0.05），但肥胖受试者的升高幅度最小（13%±1%），比对照组低60% - 70%（36%±3%，p<0.01）。数据表明，肥胖会使急性运动诱导的单核细胞胰岛素结合增加减少。