Kakihana R, Butte J C, Moore J A
Alcohol Clin Exp Res. 1980 Jan;4(1):57-61. doi: 10.1111/j.1530-0277.1980.tb04792.x.
Maternal ethanol consumption was associated with reduced levels of dihydrotestosterone in the brains of 1--2-day-old male rats when compared to those of sex-matched pups obtained from dames that were fed sucrose. In contrast, brain levels of corticosterone were increased significantly in the pups of ethanol-fed animals when compared to those from sucrose-fed controls. Brain and plasma estradiol did not differ between groups. These results suggest that maternal ethanol consumption may influence the central nervous system and plasma levels of certain steroidal hormones in the offspring.
与从喂食蔗糖的母鼠所获得的性别匹配幼崽相比，母鼠摄入乙醇会导致1至2日龄雄性大鼠大脑中的二氢睾酮水平降低。相比之下，与蔗糖喂养对照组的幼崽相比，乙醇喂养动物的幼崽大脑中的皮质酮水平显著升高。两组之间大脑和血浆中的雌二醇水平没有差异。这些结果表明，母鼠摄入乙醇可能会影响后代的中枢神经系统和某些甾体激素的血浆水平。
