N-酰基-N-2-芴基羟胺结构对芳基异羟肟酸酰基转移酶、磺基转移酶和脱酰酶活性以及对鼠伤寒沙门氏菌TA 1538中突变的影响。 - Suppr

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超能文献

Effects of structure of N-acyl-N-2-fluorenylhydroxylamines on arylhydroxamic acid acyltransferase, sulfotransferase, and deacylase activities, and on mutations in Salmonella typhimurium TA 1538.

作者信息

Weeks C E, Allaben W T, Tresp N M, Louie S C, Lazear E J, King C M

出版信息

Cancer Res. 1980 Apr;40(4):1204-11.

PMID:6986982

Abstract

摘要

相似文献

Effects of structure of N-acyl-N-2-fluorenylhydroxylamines on arylhydroxamic acid acyltransferase, sulfotransferase, and deacylase activities, and on mutations in Salmonella typhimurium TA 1538.N-酰基-N-2-芴基羟胺结构对芳基异羟肟酸酰基转移酶、磺基转移酶和脱酰酶活性以及对鼠伤寒沙门氏菌TA 1538中突变的影响。

Cancer Res. 1980 Apr;40(4):1204-11.

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Role of arylhydroxamic acid acyltransferase in the mutagenicity of N-hydroxy-N-2-fluorenylacetamide in Salmonella typhimurium.

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Activation of N-hydroxyphenacetin to mutagenic and nucleic acid-binding metabolites by acyltransfer, deacylation, and sulfate conjugation.通过酰基转移、脱酰基作用和硫酸结合作用，将N-羟基非那西丁激活为诱变和核酸结合代谢物。

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The role of acetylator genotype on hepatic and extrahepatic acetylation, deacetylation, and sulfation of 2-aminofluorene, 2-acetylaminofluorene, and N-hydroxy-2-acetylaminofluorene in the inbred hamster.乙酰化酶基因型在近交系仓鼠中对2-氨基芴、2-乙酰氨基芴和N-羟基-2-乙酰氨基芴的肝内和肝外乙酰化、去乙酰化及硫酸化作用中的角色。

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N'-hydroxy-2-aminofluorene: the principal mutagen produced from N-hydroxy-2-acetylaminofluorene by a mammalian supernatant enzyme preparation.

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Aminofluorene-DNA adduct formation in Salmonella typhimurium exposed to the carcinogen N-hydroxy-2-acetylaminofluorene.暴露于致癌物N-羟基-2-乙酰氨基芴的鼠伤寒沙门氏菌中氨基芴-DNA加合物的形成。

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引用本文的文献

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Use of 2-acetamidophenanthrene and 2-acetamidofluorene in investigations of mechanisms of hepatocarcinogenesis.2-乙酰氨基菲和2-乙酰氨基芴在肝癌发生机制研究中的应用。

Environ Health Perspect. 1983 Mar;49:81-6. doi: 10.1289/ehp.834981.

Proc Natl Acad Sci U S A. 1982 Sep;79(17):5175-8. doi: 10.1073/pnas.79.17.5175.

Comparison between carcinogenicity and mutagenicity based on chemicals evaluated in the IARC monographs.基于国际癌症研究机构（IARC）专论中评估的化学物质，对致癌性和致突变性进行比较。

Environ Health Perspect. 1983 Jan;47:305-17. doi: 10.1289/ehp.8347305.

Acetylation, deacetylation and acyltransfer.乙酰化、去乙酰化和酰基转移

Environ Health Perspect. 1983 Mar;49:43-50. doi: 10.1289/ehp.834943.

Effects of vitamin A on the metabolism and mutagenicity of 2AAF in vitro and on the covalent binding to rat liver DNA/RNA in vivo.维生素A对2-乙酰氨基芴在体外的代谢和致突变性以及在体内与大鼠肝脏DNA/RNA共价结合的影响。

Arch Toxicol. 1985 Aug;57(3):178-83. doi: 10.1007/BF00290884.

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