Thiel H
Surg Gynecol Obstet. 1980 Apr;150(4):587-92.
The hepatic circulation, which is essentially important in supplying liver cells with oxygen and substrates needed for securing metabolic homeostasis, is well regulated by extrahepatic and intrahepatic mechanisms. Autoregulation of hepatic artery flow, as well as pressure mediated vascular interactions between hepatic-arterial, portal venous and hepatovenous blood flow, secure a constant low pressure sinusoidal liver perfusion. Apart from these hemodynamic mechanisms, there are also specific morphologic features in the hepatic vascular bed responsible for regulating liver blood flow. Functional aspects concerning the arterial and portal venous contributions in liver circulation give strong evidence that portal blood may be of greater importance than arterial, especially for hepatic nutrition and trophics, as well as for metabolic homeostasis of the whole organism. In portacaval shunt operations, portal venous flow to the liver should be preserved to the greatest extent possible.
肝循环对于为肝细胞提供维持代谢稳态所需的氧气和底物至关重要，它受到肝外和肝内机制的良好调节。肝动脉血流的自身调节，以及肝动脉、门静脉和肝静脉血流之间压力介导的血管相互作用，确保了肝脏持续的低压窦状灌注。除了这些血流动力学机制外，肝血管床还具有特定的形态学特征来调节肝脏血流。关于肝循环中动脉和门静脉贡献的功能方面有力地证明，门静脉血可能比动脉血更重要，特别是对于肝脏营养和营养供应以及整个机体的代谢稳态。在门腔分流手术中，应尽可能最大程度地保留流向肝脏的门静脉血流。
