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[人癌组织和正常组织中的福斯曼抗原]

[Forssman antigen in cancerous and normal human tissues].

作者信息

Korosteleva V S, Berdinskikh M S, Kosiakov P N, Pavliuchenkova R P

出版信息

Vopr Onkol. 1980;26(2):38-41.

PMID:6987808
Abstract

By reactions of complement fixation, hemolysis and specific adsorption it was found that the heterogenous Forssman antigen is not contained in erythrocytes of normal human tissues and tumors. In the sera of healthy individuals as well as in those with cancer and benign tumors and in rabbit sera there were found complement-fixating antibodies and hemolysins being specific with regard to sheep erythrocytes (Forssman's antigen). There was noted a decreased level of heterophilic Forssman antibodies in the sera of females with malignant and benign genital tumors compared with healthy ones.

摘要

通过补体结合、溶血和特异性吸附反应发现,正常人组织和肿瘤的红细胞中不含有异质性福斯曼抗原。在健康个体、癌症患者、良性肿瘤患者的血清以及兔血清中,均发现了针对绵羊红细胞(福斯曼抗原)的补体结合抗体和溶血素。值得注意的是,与健康女性相比,患有恶性和良性生殖系统肿瘤的女性血清中嗜异性福斯曼抗体水平有所降低。

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