Holcomb G W, O'Neill J A, Holcomb G W
Ann Surg. 1980 May;191(5):626-35. doi: 10.1097/00000658-198005000-00015.
A study of 100 patients from 14 months through 18 years of age with extrahepatic biliary tract conditions who have been treated from 1950 through 1979 is reported. For discussion, these have been classified into four groups including acalculous cholecystitis, nonhemolytic cholelithiasis, hemolytic cholelithiasis and stenosis of the common duct. Ninety-nine patients were operated on and there were no deaths. Except for unusual contraindications, cholecystectomy is preferred for acute noncalculous cholecystitis. The largest number having gallstones were those patients (87%) without hemolytic disease. Only 13% had an associated hemolytic disorder. Cholecystectomy is the preferred treatment and common duct exploration is utilized when indicated. Six children with chronic relapsing pancreatitis secondary to stenosis of the ampulla of Vater and two with common duct stenosis are analyzed. Although extrahepatic biliary disorders are usually not considered in the differential diagnosis of children and adolescents with vague abdominal pain, it is evident by this large number of patients that there should be greater emphasis placed on earlier diagnosis in the future.
报告了一项对1950年至1979年期间接受治疗的100例14个月至18岁患有肝外胆道疾病的患者的研究。为便于讨论,将这些患者分为四组,包括无结石性胆囊炎、非溶血性胆石症、溶血性胆石症和胆总管狭窄。99例患者接受了手术,无死亡病例。除特殊禁忌证外,急性无结石性胆囊炎首选胆囊切除术。胆结石患者中人数最多的是那些(87%)无溶血性疾病的患者。只有13%的患者伴有溶血性疾病。胆囊切除术是首选治疗方法,如有指征则进行胆总管探查。分析了6例因 Vater壶腹狭窄继发慢性复发性胰腺炎的儿童和2例胆总管狭窄的儿童。尽管在对有模糊腹痛的儿童和青少年进行鉴别诊断时通常不考虑肝外胆道疾病,但从大量患者来看,显然未来应更加强调早期诊断。