Cartmell M T, Cusick E, Ashworth M, Duncan A, Huskisson L J
Department of Paediatric Surgery, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK.
Pediatr Surg Int. 2007 Sep;23(9):897-901. doi: 10.1007/s00383-007-1943-5.
A symptomatic pancreatic mass poses both a diagnostic and therapeutic conundrum. First, benign conditions may mimic malignancy and second, the management of benign lesions has not been well defined. We reviewed four such cases and discuss the management of juvenile idiopathic fibrosing pancreatitis in the light of these. In four children with symptomatic pancreatic masses/enlargement (three with jaundice) all resolved spontaneously without definitive intervention. Histopathology, obtained in two cases, revealed a fibrotic chronic inflammatory reaction. Pancreatic masses in children may not be malignant. Resolution of symptoms including obstructive jaundice and a mass secondary to juvenile idiopathic fibrosing pancreatitis may occur spontaneously, avoiding the need for resection or definitive drainage procedures.
有症状的胰腺肿块带来了诊断和治疗难题。首先,良性疾病可能酷似恶性肿瘤,其次,良性病变的处理尚无明确界定。我们回顾了4例此类病例,并据此讨论青少年特发性纤维性胰腺炎的处理。4例有症状的胰腺肿块/肿大患儿(3例伴有黄疸)均未经明确干预而自行缓解。2例获取的组织病理学检查显示为纤维化慢性炎症反应。儿童胰腺肿块可能并非恶性。包括梗阻性黄疸及青少年特发性纤维性胰腺炎继发肿块在内的症状可能会自行缓解,从而无需进行切除或确定性引流手术。