Obendorf D L
J Wildl Dis. 1980 Jan;16(1):135-40. doi: 10.7589/0090-3558-16.1.135.
Necropsies conducted on four young eastern grey kangaroos (Macropus giganteus) revealed white encrustations adherent to the mucosa of the lips, gums, tongue and oesophagus. The non-glandular stomach was impacted with similar white curd-like material, much of which was ahderent to the mucosa. Histopathology revealed fungal mycelia and blastospores invading the stratified squamous epithelium resulting in focal erosion, ulceration and venous thrombosis. A predominantly neutrophilic leucocytic infiltration was produced in intra-epithelial and submucosal tissues. Candida albicans was isolated from the upper alimentary tract lesions of all cases. Failure to thrive on milk diets, prolonged episodes of diarrhoea and antibiotic therapy during hand-rearing were considered to be significant predisposing factors to infection.
对四只东部灰袋鼠幼崽（大赤袋鼠）进行的尸检显示，嘴唇、牙龈、舌头和食道黏膜上附着有白色结痂。非腺胃被类似白色凝乳状物质堵塞，其中大部分附着于黏膜。组织病理学检查显示，真菌菌丝体和芽生孢子侵入复层鳞状上皮，导致局灶性糜烂、溃疡和静脉血栓形成。上皮内和黏膜下组织出现以嗜中性白细胞为主的白细胞浸润。所有病例的上消化道病变均分离出白色念珠菌。以牛奶为食时生长不良、人工饲养期间长期腹泻和抗生素治疗被认为是感染的重要诱发因素。
