破伤风疫苗接种后血液中的人类淋巴细胞群体。

Human lymphocyte populations in blood after tetanus vaccination.

作者信息

Enk C, Jønsson V, Christensen B E

出版信息

Scand J Haematol. 1980 Feb;24(2):181-6. doi: 10.1111/j.1600-0609.1980.tb02365.x.

DOI:10.1111/j.1600-0609.1980.tb02365.x

Abstract

The content of circulating T and B lymphocytes in 9 healthy volunteers was estimated before and after secondary vaccination with tetanus toxoid. E, Fc, and C3 receptors were demonstrated by rosette techniques and surface Ig by fluorescence technique. The absolute number of T and non-T (B) lymphocytes was simultaneously increased during the first 48 h and at 144 h after vaccination. The correlation between paired T and non-T (B) lymphocyte counts was enhanced after vaccination, probably reflecting mechanisms governing the traffic of lymphocytes.

摘要

在9名健康志愿者二次接种破伤风类毒素前后，对其循环T淋巴细胞和B淋巴细胞的含量进行了评估。通过玫瑰花结技术检测E、Fc和C3受体，通过荧光技术检测表面免疫球蛋白。接种疫苗后的头48小时以及144小时，T淋巴细胞和非T（B）淋巴细胞的绝对数量同时增加。接种疫苗后，配对的T淋巴细胞计数和非T（B）淋巴细胞计数之间的相关性增强，这可能反映了淋巴细胞迁移的调控机制。