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[克雷伯菌肺炎中的大片肺坏死(所谓的大片肺坏疽)]

[Massive lung necrosis in klebsiella pneumonia (so-called massive lung gangrene)].

作者信息

Schamaun M, von Büren U, Pirozynski W

出版信息

Schweiz Med Wochenschr. 1980 Feb 9;110(6):223-5.

PMID:6990484
Abstract

In the literature only 13 cases of voluminous necrosis of lung tissue, generally referred to as massive pulmonary gangrene, could be found. This disease constitutes an unusual, very severe complication of lobar pneumonia, mostly due to Klebsiella. This type of pneumonia generally affects old or otherwise debilitated persons, quite often chronic alcoholics. It has a high lethality of 20%. Our own observation in a 48-year-old man is presented. He suffered from recurrent massive hemoptysis in relation with a huge cavity of the right lung, filled with necrotic lung tissue. Following right pneumonectomy empyema developed, also due to Klebsiella; it was successfully treated with thoracic fenestration according to Clagett. Knowledge of this severe infrequent complication of pneumonia is necessary since it requires early operative treatment: Out of the 14 patients four were treated medically only and died, while the remaining ten underwent surgery and were all cured.

摘要

在文献中仅能找到13例肺组织大量坏死的病例,一般称为大块肺坏疽。这种疾病是大叶性肺炎一种罕见且非常严重的并发症,主要由克雷伯菌引起。此类肺炎通常影响老年人或其他身体虚弱者,相当常见于慢性酗酒者。其致死率高达20%。本文介绍了我们对一名48岁男性患者的观察情况。他因右肺有一个充满坏死肺组织的巨大空洞而反复大量咯血。右肺切除术后发生了同样由克雷伯菌引起的脓胸;根据克拉吉特法进行胸廓开窗术成功治愈。了解这种肺炎严重且罕见的并发症很有必要,因为它需要早期手术治疗:14例患者中4例仅接受药物治疗并死亡,其余10例接受了手术且全部治愈。

相似文献

1
[Massive lung necrosis in klebsiella pneumonia (so-called massive lung gangrene)].[克雷伯菌肺炎中的大片肺坏死(所谓的大片肺坏疽)]
Schweiz Med Wochenschr. 1980 Feb 9;110(6):223-5.
2
Massive necrotizing pneumonia with pulmonary gangrene.伴有肺坏疽的大面积坏死性肺炎。
Ann Thorac Surg. 2009 Jan;87(1):310-1. doi: 10.1016/j.athoracsur.2008.05.077.
3
Massive pulmonary gangrene: a severe complication of Klebsiella pneumonia.大面积肺坏疽:克雷伯菌肺炎的一种严重并发症。
Can Med Assoc J. 1975 Jan 25;112(2):196-8.
4
Massive pulmonary gangrene.大面积肺坏疽
South Med J. 1977 Sep;70(9):1144-6. doi: 10.1097/00007611-197709000-00044.
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Pulmonary gangrene complicating bacterial pneumonia.并发细菌性肺炎的肺坏疽
Indian Pediatr. 2003 Aug;40(8):784-5.
6
Use of ECMO for resection of post-traumatic ruptured lung abscess with empyema.使用体外膜肺氧合(ECMO)切除创伤后破裂性肺脓肿伴脓胸。
Ann Thorac Surg. 2010 Dec;90(6):2039-41. doi: 10.1016/j.athoracsur.2010.01.085.
7
Surgical therapy for necrotizing pneumonia and lung gangrene.坏死性肺炎和肺坏疽的外科治疗
Thorac Cardiovasc Surg. 2013 Oct;61(7):636-41. doi: 10.1055/s-0032-1311551. Epub 2012 Oct 3.
8
Chronic Klebsiella pneumonia in an immunocompetent host.
J Assoc Physicians India. 2003 Mar;51:306-8.
9
Letter: Massive pulmonary gangrene.信函:大面积肺坏疽。
Can Med Assoc J. 1975 Jun 7;112(11):1290.
10
Pneumonectomy for unilateral destroyed lung with pulmonary hypertension due to systemic blood flow through broncho-pulmonary shunts.因体循环血流经支气管肺分流导致肺动脉高压而行单侧毁损肺肺切除术。
Eur J Cardiothorac Surg. 2005 Sep;28(3):389-93. doi: 10.1016/j.ejcts.2005.04.044.

引用本文的文献

1
Survival with optimal medical management in a cohort of severe necrotizing bacterial lung infections.一组严重坏死性细菌性肺部感染患者接受最佳药物治疗后的生存情况。
J Thorac Dis. 2023 Jul 31;15(7):3860-3869. doi: 10.21037/jtd-22-1590. Epub 2023 Jul 20.
2
Surgical management of acute necrotizing lung infections.急性坏死性肺部感染的外科治疗
Can Respir J. 2006 Oct;13(7):369-73. doi: 10.1155/2006/760390.
3
Therapeutic activities of cefazolin, cefotaxime, and ceftazidime against experimentally induced Klebsiella pneumoniae pneumonia in rats.
头孢唑林、头孢噻肟和头孢他啶对大鼠实验性肺炎克雷伯菌肺炎的治疗活性。
Antimicrob Agents Chemother. 1982 Dec;22(6):1042-50. doi: 10.1128/AAC.22.6.1042.