Schilling A
Urol Int. 1980;35(2):141-5. doi: 10.1159/000280313.
The renin activity of the juxtaglomerular apparatus following a period of 210 min of hemorrhagic hypotension was correlated with the blood volume retransfused in order to maintain a hypotensive blood pressure of 30 mm Hg. In an additional experiment the renin activity of the juxtaglomerular apparatus was measured in acute renal failure due to renal artery occlusion over 60 min. The increased renin activity after hemorrhagic hypotension indicates that the renin-angiotensin system contributes to pressure stabilization. The similar rise of the juxtaglomerular renin activity in hypotension as well as in renal artery occlusion suggests the active role of the renin-angiotensin system in acute renal failure following severe hemorrhagic hypotension.
在经历210分钟失血性低血压后，肾小球旁器的肾素活性与为维持30毫米汞柱的低血压而回输的血容量相关。在另一项实验中，测量了因肾动脉闭塞60分钟导致急性肾衰竭时肾小球旁器的肾素活性。失血性低血压后肾素活性增加表明肾素-血管紧张素系统有助于血压稳定。低血压以及肾动脉闭塞时肾小球旁器肾素活性的类似升高表明肾素-血管紧张素系统在严重失血性低血压后的急性肾衰竭中起积极作用。
