Andrews R E, Spence K D, Miller L K
Appl Environ Microbiol. 1980 Apr;39(4):932-3. doi: 10.1128/aem.39.4.932-933.1980.
The relative virulence of five different genotypic variants of Autographa californica nuclear polyhedrosis virus was tested by determining the 50% lethal dose of occluded virus for larvae of Trichoplusia ni. The 50% lethal dose values of uncloned virus and the five cloned genotypic variants ranged between 10 and 21 polyhedra per larva, and no statistically significant differences were observed. Cloning has therefore neither enhanced nor decreased the virulence of this potential microbial pesticide.
通过测定苜蓿银纹夜蛾核型多角体病毒的50%致死剂量,对苜蓿银纹夜蛾核型多角体病毒五种不同基因型变体的相对毒力进行了测试。未克隆病毒和五种克隆基因型变体的50%致死剂量值在每头幼虫10至21个多角体之间,未观察到统计学上的显著差异。因此,克隆既未增强也未降低这种潜在微生物杀虫剂的毒力。