Vincendeau P, Claudy A, Thivolet J, Tessier R, Texier L
Arch Dermatol. 1980 Jun;116(6):681-2.
A case of a recurrent bullous eruption in a patient who had myeloma is reported. This eruption was differentiated from pemphigus and bullous pemphigoid by the histological and immunological findings. In addition, antibodies against the cytoplasm of basal cell layer cells in the human epidermis were detected in the patient's serum and in diseased skin. The myelomatous monoclonal protein and the antibody fixed on the cell cytoplasm had an identifical isotypical marker.
报告了一例患有骨髓瘤的患者反复出现大疱性皮疹的病例。通过组织学和免疫学检查结果,将这种皮疹与天疱疮和大疱性类天疱疮区分开来。此外,在患者血清和患病皮肤中检测到针对人表皮基底细胞层细胞质的抗体。骨髓瘤单克隆蛋白和固定在细胞质上的抗体具有相同的同型标记。