Jara F M, Toledo-Pereyra L H, Lewis J W, Magilligan D J
Ann Thorac Surg. 1980 May;29(5):483-8. doi: 10.1016/s0003-4975(10)61686-4.
At the present time, the major obstacles in the successful clinical application of heart transplantation are the immunological attack on the allograft, the treatment of complications resulting from immunosuppression, and the supply of transplantable hearts. Recently, auxiliary heart transplantation has been proved to be a successful technique for treatment of end-stage myocardial failure in humans. Here we review the experimental work in auxiliary heart transplantation leading to the present technique used in humans.
目前,心脏移植在临床成功应用的主要障碍是对同种异体移植物的免疫攻击、免疫抑制引起的并发症的治疗以及可移植心脏的供应。最近,辅助性心脏移植已被证明是治疗人类终末期心肌衰竭的一种成功技术。在此,我们回顾了导致目前人类使用的辅助性心脏移植技术的实验工作。