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Synthesis, crystallization and properties of acetyl phenylalanyl lysine chloromethyl ketone: a potential inhibitor of serine proteases.

作者信息

Murthy V V, Laster T

出版信息

Experientia. 1980 Apr 15;36(4):397-8. doi: 10.1007/BF01975108.

Abstract

A procedure for the synthesis of acetyl phenylalanyl lysine chloromethyl ketone is described. The chloromethyl ketone derivative is a noncompetitive inhibitor of trypsin (Ki = 5.9 x 10(-3) M).

摘要

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