Turpin F, Lejeune F, Lortholary P
Pathol Biol (Paris). 1980 May;28(5):305-11.
The authors report a case of acute myeloid leukemia developping 5 years after the onset of an autoimmune hemolytic anemia. The cytological origin of the proliferation is difficult to assess: the presence of prominent membranous complexes and a strong positivity of acid phosphatase reaction favour its megacaryocytic origin. However the cytological evolution pleads for the development of successive clones of monocytic origin, may be modified by the treatment. Are the two diseases successive consequences of preexisting state of immunodepression or was such a state created by the autoimmune anemia?
作者报告了1例自身免疫性溶血性贫血发病5年后发生急性髓系白血病的病例。增殖的细胞学起源难以评估：显著膜性复合物的存在及酸性磷酸酶反应强阳性支持其巨核细胞起源。然而，细胞学演变提示单核细胞起源的连续克隆的发展，可能因治疗而改变。这两种疾病是先前免疫抑制状态的连续后果，还是这种状态由自身免疫性贫血所致？
