D'Amelio R, LeMoli S, Rossi P, Aiuti F
Scand J Immunol. 1980;11(5):471-7. doi: 10.1111/j.1365-3083.1980.tb00015.x.
The chemotactic and random mobility functions of twelve selectively IgA-deficient patients were evaluated by a method using agarose gel. A severe polymorphonuclear cellular chemotactic defect was found in ten out of twelve patients, but only five of them also showed a marked associated impairment of random locomotory function. Furthermore, in one subject, levamisole therapy resulted in a dramatic improvement of both chemotactic and random mobility functions. These results are discussed in the paper with respect to the possible pathogenetic implications.
采用琼脂糖凝胶法对12例选择性IgA缺乏患者的趋化和随机移动功能进行了评估。12例患者中有10例存在严重的多形核细胞趋化缺陷，但其中只有5例同时伴有明显的随机运动功能障碍。此外，在1例患者中，左旋咪唑治疗使趋化和随机移动功能都得到了显著改善。本文就这些结果的可能发病机制进行了讨论。
