Mutagenicity of dichloroacetate, an ingredient of some formulations of pangamic acid (trade-named "vitamin B15").
作者信息
Herbert V, Gardner A, Colman N
出版信息
Am J Clin Nutr. 1980 Jun;33(6):1179-82. doi: 10.1093/ajcn/33.6.1179.
PMID:6992558
Abstract
Dichloroacetate demonstrates low grade mutagenicity in the Ames Salmonella/mammaltan microsome mutagenicity test. This evidence of probable carcinogenicity must be considered in any proposed use of dichloroacetate or of preparations of pangamic acid (trade-named "vitamin B15") CONTAINING DICHLOROACETATE.
摘要
相似文献
1
Mutagenicity of dichloroacetate, an ingredient of some formulations of pangamic acid (trade-named "vitamin B15").
Am J Clin Nutr. 1980 Jun;33(6):1179-82. doi: 10.1093/ajcn/33.6.1179.
2
Mutagenicity of diisopropylamine dichloroacetate, the "active constituent" of vitamin B15 (pangamic acid).
Nutr Cancer. 1982;3(3):129-33. doi: 10.1080/01635588109513714.
3
[Autopsy of a phantom: pangamic acid, alias vitamin B15].
Schweiz Z Sportmed. 1983 Jun;31(2):45-51.
4
Transmethylation in cardiopathies: the role of pangamic acid (vitamin B15).
J Am Osteopath Assoc. 1960 Aug;59:968-71.
5
Vitamin B15--whatever it is, it won't help.
JAMA. 1980 Jun 27;243(24):2473, 2480. doi: 10.1001/jama.243.24.2473.
6
Critical evaluation of the current studies on pangamic acid--vitamin B15.
Nahrung. 1982;26(4):363-7. doi: 10.1002/food.19820260405.
7
[Existence of "pangamic acid" alias "vitamin B 15"?].
Fortschr Med. 1984 Mar 29;102(12):339-41.
8
Effects of commercial preparations of pangamic acid (B15) on exercised rats.
Biochem Med. 1982 Aug;28(1):77-82. doi: 10.1016/0006-2944(82)90057-6.
9
Detection of the carcinogenic nitrofuran derivative VR-6 as a mutagen in the Salmonella/microsome test.
Arch Toxicol. 1979 Sep;42(4):259-64. doi: 10.1007/BF00334839.
10
[Pangamic acid (vitamin B-15), its nature, properties and production].
Vopr Med Khim. 1962 May-Jun;8:236-8.
引用本文的文献
1
The immunomodulatory effects of vitamins in cancer.维生素在癌症中的免疫调节作用。
Front Immunol. 2024 Oct 7;15:1464329. doi: 10.3389/fimmu.2024.1464329. eCollection 2024.
2
Mode of action of liver tumor induction by trichloroethylene and its metabolites, trichloroacetate and dichloroacetate.三氯乙烯及其代谢产物三氯乙酸和二氯乙酸诱导肝肿瘤的作用模式。
Environ Health Perspect. 2000 May;108 Suppl 2(Suppl 2):241-59. doi: 10.1289/ehp.00108s2241.
Zotero 插件