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小儿肾移植受者的水痘-带状疱疹感染

Varicella-zoster infections in pediatric renal transplant recipients.

作者信息

Hurley J K, Greenslade T, Lewy P R, Ahmadian Y, Firlit C

出版信息

Arch Surg. 1980 Jun;115(6):751-2. doi: 10.1001/archsurg.1980.01380060049012.

Abstract

Varicella-zoster infections developed in ten of 76 children receiving a renal transplant during 1973 to 1978. Two children had varicella and one died during this infection. Eight children had herpes zoster and one experienced encephalitis. In the latter group, reduction of prednisone and azathioprine therapy resulted in rejection and loss of the graft in two of three patients in whom this drug therapy was altered.

摘要

1973年至1978年期间接受肾移植的76名儿童中有10名发生了水痘 - 带状疱疹感染。两名儿童患了水痘,其中一名在感染期间死亡。八名儿童患了带状疱疹,一名发生了脑炎。在后一组中,三名改变了泼尼松和硫唑嘌呤治疗方案的患者中有两名因减少了这种药物治疗而发生排斥反应并失去了移植肾。

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