Waters K J, Craxford A D, Chamberlain J
Br J Surg. 1980 May;67(5):349-51. doi: 10.1002/bjs.1800670516.
In a randomized double-blind controlled trial the effect of naftidrofuryl (Praxilene) 200 mg t.d.s., taken for 6 months, was compared with placebo in intermittent claudication. Whilst there was a significant subjective improvement regardless of age or treatment, patients over 60 on naftidrofuryl experienced a more rapid symptomatic relief than other patients. At six months this age group showed a significant improvement over the placebo group. There was no significnat objective evidence of improvement.
在一项随机双盲对照试验中，将200毫克萘呋胺酯（脉管复康）每日三次服用6个月的效果与安慰剂用于间歇性跛行的情况进行了比较。尽管无论年龄或治疗情况如何都有显著的主观改善，但60岁以上服用萘呋胺酯的患者比其他患者症状缓解得更快。在6个月时，该年龄组与安慰剂组相比有显著改善。没有明显的客观改善证据。
