奥硝唑预防腹式子宫切除术后感染
Ornidazole in the prevention of infections after abdominal hysterectomy.
作者信息
Stocklund K E, Kessel M, Jensen R H
出版信息
Chemotherapy. 1980;26(5):397-401. doi: 10.1159/000237932.
PMID:6993112
Abstract
Following informed consent, 226 consecutive patients scheduled to undergo abdominal hysterectomy entered a randomized double-blind clinical trial to determine the efficacy of ornidazole versus placebo in the prevention of postoperative infections. Postoperative abscesses occurred in 2 patients (1.8%) in the ornidazole group compared to 5 patients (4.4% in the placebo group. Febrile episodes occurred in 6 patients (5.3% receiving ornidazole and in 13 patients (11.4%) receiving placebo.
摘要
在获得知情同意后，226例计划接受腹式子宫切除术的连续患者进入一项随机双盲临床试验，以确定奥硝唑与安慰剂在预防术后感染方面的疗效。奥硝唑组有2例患者（1.8%）发生术后脓肿，而安慰剂组有5例患者（4.4%）发生。接受奥硝唑治疗的6例患者（5.3%）出现发热，接受安慰剂治疗的13例患者（11.4%）出现发热。
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