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奥硝唑预防腹式子宫切除术后感染

Ornidazole in the prevention of infections after abdominal hysterectomy.

作者信息

Stocklund K E, Kessel M, Jensen R H

出版信息

Chemotherapy. 1980;26(5):397-401. doi: 10.1159/000237932.

DOI:10.1159/000237932
PMID:6993112
Abstract

Following informed consent, 226 consecutive patients scheduled to undergo abdominal hysterectomy entered a randomized double-blind clinical trial to determine the efficacy of ornidazole versus placebo in the prevention of postoperative infections. Postoperative abscesses occurred in 2 patients (1.8%) in the ornidazole group compared to 5 patients (4.4% in the placebo group. Febrile episodes occurred in 6 patients (5.3% receiving ornidazole and in 13 patients (11.4%) receiving placebo.

摘要

在获得知情同意后,226例计划接受腹式子宫切除术的连续患者进入一项随机双盲临床试验,以确定奥硝唑与安慰剂在预防术后感染方面的疗效。奥硝唑组有2例患者(1.8%)发生术后脓肿,而安慰剂组有5例患者(4.4%)发生。接受奥硝唑治疗的6例患者(5.3%)出现发热,接受安慰剂治疗的13例患者(11.4%)出现发热。

相似文献

1
Ornidazole in the prevention of infections after abdominal hysterectomy.奥硝唑预防腹式子宫切除术后感染
Chemotherapy. 1980;26(5):397-401. doi: 10.1159/000237932.
2
[Comparative study of tinidazole and ornidazole for the prevention of septic complications of colonic surgery].替硝唑与奥硝唑预防结肠手术感染性并发症的对比研究
Pathol Biol (Paris). 1983 Jun;31(6):509-11.
3
[Prophylactic and therapeutic effect of ornidazole (Tiberal Roche) in abdominal surgery].奥硝唑(替硝唑,罗氏公司生产)在腹部手术中的预防和治疗作用
Rozhl Chir. 1985 Jun;64(6):451-6.
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[Prophylactic use of ornidazole in digestive surgery in neonates and children].[奥硝唑在新生儿及儿童消化外科手术中的预防性应用]
LARC Med. 1982 Mar;2(3):260-3.
5
[Evaluation of the use of the combination sulfamethoxazole-trimethoprim-ornidazole in the prevention of infections in major ORL surgery and otoneurosurgery (on 100 cases)].
Rev Laryngol Otol Rhinol (Bord). 1985;106(3):221-4.
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Ornidazole versus clindamycin: comparative evaluation in the treatment of 140 serious anaerobic infections.奥硝唑与克林霉素:140例严重厌氧菌感染治疗的比较评价
Chemotherapy. 1982;28(6):502-11. doi: 10.1159/000238140.
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Minute treatment with tinidazole and ornidazole in children with amebic dysentery.用替硝唑和奥硝唑对患阿米巴痢疾的儿童进行短程治疗。
Paediatr Indones. 1982 Jul-Aug;22(7-8):132-5.
8
Single-dose intravenous tinidazole prophylaxis in abdominal hysterectomy.腹部子宫切除术中单剂量静脉注射替硝唑预防感染
Acta Obstet Gynecol Scand. 1986;65(4):361-5. doi: 10.3109/00016348609157361.
9
Management of surgical infections.外科感染的管理
Scand J Gastroenterol Suppl. 1984;90:71-5.
10
Double-blind randomized comparative trial: ornidazole (Tiberal) versus tinidazole (Fasigin) for the treatment of non-specific vaginitis.
Chemioterapia. 1985 Jun;4(3):218-21.

引用本文的文献

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Antibiotic prophylaxis for elective hysterectomy.择期子宫切除术的抗生素预防
Cochrane Database Syst Rev. 2017 Jun 18;6(6):CD004637. doi: 10.1002/14651858.CD004637.pub2.