Tepper T, van der Hem G K, Tuma G J, Arisz L, Donker A J
Clin Nephrol. 1978 Jul;10(1):16-20.
In three patients the total amino acid losses (free plus peptide-bound) in dialyzate have been assayed by means of gas-liquid chromatography. During a period 3--4 months the average losses varied from 115--178 mg per kg of body weight per dialysis treatment. The weekly mean essential amino acid losses amounted to 3--4% of the dietary intake. The concentrations in the dialyzate of non-essential amino acid fell considerably during the dialysis procedure, whereas the concentrations of most of the essential amino acids remained at a fairly constant level. It is concluded that considerable quantitative but no qualitative differences exist between the patients with respect to amino acid losses.
通过气液色谱法测定了3例患者透析液中的总氨基酸损失量（游离氨基酸加肽结合氨基酸）。在3至4个月的时间里，每次透析治疗每千克体重的平均损失量在115至178毫克之间。每周必需氨基酸的平均损失量占饮食摄入量的3%至4%。在透析过程中，透析液中非必需氨基酸的浓度大幅下降，而大多数必需氨基酸的浓度则保持在相当稳定的水平。得出的结论是，患者之间在氨基酸损失方面存在相当大的量的差异，但没有质的差异。
