Kim E E, DeLand F H
Clin Nucl Med. 1978 Aug;3(8):328-30. doi: 10.1097/00003072-197808000-00008.
In two children with histoplasmosis pulmonary perfusion and ventilation studies revealed mismatched abnormalities characterized by almost unilaterally absent perfusion but normal ventilation in the right lung. Chest roentgenograms demonstrated right hilar enlargement and pulmonary contrast angiograms revealed narrowing of the right pulmonary arteries by extrinsic fibrotic granulomata but no pulmonary emboli were present. Fibrosing mediastinitis due to histoplasmosis was found by mediastinoscopic examination in one of the patients. Non-embolic causes of V/Q mismatch lung imaging are discussed briefly, and the correlation with clinical findings is stressed for the diagnosis of pulmonary emboli.
在两名组织胞浆菌病患儿中,肺灌注和通气研究显示不匹配异常,表现为右肺几乎单侧灌注缺失但通气正常。胸部X线片显示右肺门增大,肺血管造影显示右肺动脉被外在纤维化肉芽肿压迫变窄,但未发现肺栓塞。其中一名患者经纵隔镜检查发现由组织胞浆菌病引起的纤维性纵隔炎。简要讨论了通气/灌注不匹配肺部成像的非栓塞原因,并强调了其与临床发现的相关性对肺栓塞诊断的重要性。