Randall L L, Josefsson L G, Hardy S J
Eur J Biochem. 1980 Jun;107(2):375-9. doi: 10.1111/j.1432-1033.1980.tb06039.x.
Nascent intermediates in the synthesis of maltose-binding protein, a periplasmic protein in Escherichia coli, were demonstrated both in vivo and in vitro. They are likely to result from a drastic reduction in the rate of elongation at specific sites on the mRNA leading to detectable accumulation of distinct species of incomplete polypeptides. In order to reach its final destination in the periplasmic space, maltose-binding protein is transferred across the cytoplasmic membrane as it is elongated. It is possible that variations in the rate of elongation are involved in this export process.
麦芽糖结合蛋白是大肠杆菌周质中的一种蛋白质，其合成过程中的新生中间体已在体内和体外得到证实。它们可能是由于mRNA特定位点上延伸速率急剧降低，导致不同种类的不完全多肽可检测地积累。为了到达周质空间的最终目的地，麦芽糖结合蛋白在延伸过程中穿过细胞质膜。延伸速率的变化可能参与了这个输出过程。
