Klostergaard J, Evans J T, Fonte G C, Lane W W, Laor Y, Klein E, Holtermann O A
J Med. 1980;11(1):49-63.
The effect of serum of patients with solid tumors on the phagocytic activity of normal neutrophilic granulocytes was investigated. The largest groups of tumors studied were carcinoma of colon/rectum, sarcomas and melanomas. Sera from all three groups of patients were found to have highly significant (p < 0.001) stimulatory effects on granulocyte phagocytic activity. These findings contrast with previously reported depression of granulocyte phagocytic activity associated with various forms of leukemia and lymphomas.
研究了实体瘤患者血清对正常中性粒细胞吞噬活性的影响。所研究的肿瘤中，数量最多的是结肠/直肠癌、肉瘤和黑色素瘤。发现这三组患者的血清对粒细胞吞噬活性均有高度显著（p < 0.001）的刺激作用。这些发现与先前报道的与各种形式白血病和淋巴瘤相关的粒细胞吞噬活性降低形成对比。
